Scientific Publications

ECM and ECM- like materials – Ideal biomaterials for applications in regenerative medicine and cancer therapy

ECM and ECM- like materials – Ideal biomaterials for applications in regenerative medicine and cancer therapy

Regenerative strategies such as stem cell-based therapies and tissue engineering applications are being developed with the aim to replace, remodel, regenerate or support damaged tissues and organs.

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Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives

Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives

Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy has progressed considerably from clinical and preclinical studies delivering simple suspensions of cells, macromolecule, and small molecules to more advanced delivery methods utilizing biomaterial scaffolds as depots for localized targeted delivery to the damaged and ischemic myocardium.

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A minimally invasive endocradial catheter for delivery of stem cells embedded in fast-gelling hyaluronic acid hydrogels

Main author: Dolan E., Kohutova L., O'Neill H., Prvada M., Sulakova R., Daro D., Braun N., Cooney G., Bllavia G., Straino S., Kavanagh L., Flanagan A., Kelly H., Daffy G., Mur

“Design and development of a minimally invasive endocardial delivery device for fast-gelling hyaluronic acid hydrogels for the treatment of myocardial infarction”

Main author: Eimear B. Dolan, Lenka Kohutova, Hugh O’Neill, Brenton L. Kavanagh, Dorothee Daro, Gerard Cooney, Helena Kelly, Bruce P. Murphy and Garry P. Duffy

Attended Events

Conference of the European Society for Biomaterials

Conference of the European Society for Biomaterials

The AMCARE project has participated in the 28th Annual Conference of the European Society for Biomaterials (ESB) in Athens 4-8 September 2017. The conference took place in the Megaron Athens International Conference Center (MAICC), located at the heart of the city of Athens.

European Society for Biomaterials (ESB)  2017

European Society for Biomaterials (ESB) 2017

CONTIPRO has participated in one of the world's most important events for the biomaterials science community. ESB 2017 was held in Athens in September 2017. The CONTIPRO researchers, during the 5 days event, had 2 lectures and 6 scientific posters about AMCARE project.

AMCARE project presented at Science and Innovation Fair 2017

AMCARE project presented at Science and Innovation Fair 2017

CONTIPRO presented AMCARE project at the Science and Innovation Fair which took place in Brno (Czech Republic) from the 28th february to the 2nd march 2017 .

WINTER SCHOOL: TRAINING EVENT

WINTER SCHOOL: TRAINING EVENT

The AMCARE project in association with sister EU projects DRIVE and NEXT organised a Winter School training event: "Translational Reality of Advanced Therapy Medicinal Products (ATMPs)" in the Galway Bay Hotel from November 28th – December 1st 2016. All three projects are focused on the development of ATMPs (cell therapy products).

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SCI:COM Communicating Irish Science

SCI:COM Communicating Irish Science

SCI:COM 2015 was a new, all-Ireland science communication conference. SCI:COM was an unmissable event for science communication to any audience, researcher, event organiser, teacher, journalist, or work behind the scenes in STEM administration. SCI:COM develops skills for effective science communication in breakout sessions delivered by experienced professionals from a wide range of disciplines.

National Ploughing Association, 23rd September 2015 Dublin

National Ploughing Association, 23rd September 2015 Dublin

National Ploughing Association, 23rd September 2015 Dublin, Ireland: In September 2015, Science Foundation Ireland (SFI) supported and funded AMCARE’s “Mending Broken Hearts” demonstration at the National Ploughing Championships (http://www.npa.ie/). Recently SFI have shown how important outreach and public engagement is in informing the public of the importance of scientific research, to demystify it while also illustrating its huge value to society. A great day was had at the Ploughing Championships! We got to speak to hundreds of people about AMCARE's fascinating research and show them why and how we are doing the work we do. Everybody knows somebody who has suffered a heart attack or suffers from heart disease which is why it is so important to get to reach out to the public and show them the research that is currently being carried out. It was of huge benefit to get the opportunity to showcase in this setting as the 2015 championships were the most popular year yet with 281,000 visitors over the 3 days. Over the course of the day, AMCARE researchers spoke to approximately 1000 people. We were able to reach out to children, their parents, teenagers visiting with their schools and older people all interested in the varying aspects of our research.

DISCOVER RESEARCH DUBLIN 2014

DISCOVER RESEARCH DUBLIN 2014

On the evening of the 26th September 2014, AMCARE researchers took part in Discover Research Dublin 2014, an interactive night of public engagement on wide variety of research themes. The initiative was funded by the European Commission's Research and Innovation Framework Programme H2020 (2014-2020) and was hosted by Trinity College Dublin (TCD), in partnership with the Royal College of Surgeons in Ireland (RCSI)...

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AMCARE Outreach Event - Discover Research Night

by Conn Hastings (RCSI)

On the evening of the 26th September 2014, AMCARE researchers took part in Discover Research Dublin 2014, an interactive night of public engagement on wide variety of research themes.

The initiative was funded by the European Commission's Research and Innovation Framework Programme H2020 (2014-2020) and was hosted by Trinity College Dublin (TCD), in partnership with the Royal College of Surgeons in Ireland (RCSI).

The AMCARE stand was aptly entitled ‘Mending Broken Hearts’ and consisted of interactive models, experiments, a slide show and poster presentations. The overall goal of the event was to provide an overview of the activities of researchers in both TCD and RCSI, for both entertainment and educational purposes. This engagement was intended to demystify scientific research while illustrating its potential value to society. The event facilitated direct public contact with researchers, to allow for questions and participation.

The night was a huge success and the AMCARE stand was very popular. The AMCARE team discussed various facets of our day to day work. We illustrated the mechanism behind a myocardial infarction (MI) and why current treatments are often suboptimal. The team outlined our proposal in general terms and explained how it could potentially improve the lives of MI patients. Dr. Aamir Hameed, a cardiothoracic surgeon and AMCARE research assistant, demonstrated on a full scale model of a human torso, the method of insertion, path of deployment and site of delivery of a trans-vascular injection catheter. Liam McDonagh, a Pharmacy student completing a Masters project with the AMCARE team, demonstrated the use and action of cross-linkable hydrogels with an interactive experiment in which the public could participate. The response was overwhelmingly positive, and the team was encouraged by the level of public interest and engagement.

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